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Article

Heterozygote Advantage Is a Common Outcome of Adaptation in Saccharomyces cerevisiae.

Genetics - 1 Jul 2016

Sellis Diamantis, Kvitek Daniel J, Dunn Barbara, Sherlock Gavin, Petrov Dmitri A

Abstract excerpt

Adaptation in diploids is predicted to proceed via mutations that are at least partially dominant in fitness. Recently, we argued that many adaptive mutations might also be commonly overdominant in fitness. Natural (directional) selection acting on overdominant mutations should drive them into the population but then, instead of bringing them to fixation, should maintain them as balanced polymorphisms via...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 27194750
DOI: 10.1534/genetics.115.185165
PMCID: PMC4937471

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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