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Article

The cytosolic Fe-S cluster assembly component MET18 is required for the full enzymatic activity of ROS1 in active DNA demethylation.

Scientific reports - 19 May 2016

Wang Xiaokang, Li Qi, Yuan Wei, Cao Zhendong, Qi Bei, Kumar Suresh, Li Yan, Qian Weiqiang

Abstract excerpt

DNA methylation patterns in plants are dynamically regulated by DNA methylation and active DNA demethylation in response to both environmental changes and development of plant. Beginning with the removal of methylated cytosine by ROS1/DME family of 5-methylcytosine DNA glycosylases, active DNA demethylation in plants occurs through base excision repair. So far, many components involved in active DNA demethylation...

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Identifiers

PMID: 27193999
DOI: 10.1038/srep26443
PMCID: PMC4872223

Genes

ROS1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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