Article
Parallel Evolution in Streptococcus pneumoniae Biofilms.
Genome biology and evolution - 9 May 2016
Churton Nicholas W V, Misra Raju V, Howlin Robert P, Allan Raymond N, Jefferies Johanna, Faust Saul N, Gharbia Saheer E, Edwards Richard J, Clarke Stuart C, Webb Jeremy S
Abstract excerpt
Streptococcus pneumoniae is a commensal human pathogen and the causative agent of various invasive and noninvasive diseases. Carriage of the pneumococcus in the nasopharynx is thought to be mediated by biofilm formation, an environment where isogenic populations frequently give rise to morphological colony variants, including small colony variant (SCV) phenotypes. We employed metabolic characterization and...
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