Article
Strain-specific parallel evolution drives short-term diversification during Pseudomonas aeruginosa biofilm formation.
Proceedings of the National Academy of Sciences of the United States of America - 8 Apr 2014
McElroy Kerensa E, Hui Janice G K, Woo Jerry K K, Luk Alison W S, Webb Jeremy S, Kjelleberg Staffan, Rice Scott A, Thomas Torsten
Abstract excerpt
Generation of genetic diversity is a prerequisite for bacterial evolution and adaptation. Short-term diversification and selection within populations is, however, largely uncharacterised, as existing studies typically focus on fixed substitutions. Here, we use whole-genome deep-sequencing to capture the spectrum of mutations arising during biofilm development for two Pseudomonas aeruginosa strains. This approach...
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