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Genomic and transcriptomic characterization of Pseudomonas aeruginosa small colony variants derived from a chronic infection model

28 Mar 2019

Abstract excerpt

Phenotypic change is a hallmark of bacterial adaptation during chronic infection. In the case of chronic Pseudomonas aeruginosa lung infection in patients with cystic fibrosis, well-characterized phenotypic variants include mucoid and small colony variants (SCVs). It has previously been shown that SCVs can be reproducibly isolated from the murine lung following the establishment of chronic infection with mucoid...

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PMID: 30920365
DOI: 10.1099/mgen.0.000262

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