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Article

Parallel evolution of small colony variants in Burkholderia cenocepacia biofilms.

Genomics - 1 Dec 2014

Cooper Vaughn S, Staples Rachel K, Traverse Charles C, Ellis Crystal N

Abstract excerpt

A common phenotype within bacterial biofilms is the small, "wrinkly" colony, which may associate with worse prognoses from biofilm-associated infections. The mechanisms that produce these variants in Burkholderia are undefined. Here we report the mutational and ecological causes of wrinkly (W) colonies that evolved during experimental biofilm evolution of Burkholderia cenocepacia. Mutations clustered in a...

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PMID: 25263109
DOI: 10.1016/j.ygeno.2014.09.007

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