Article
Breaking Good: Accounting for Fragility of Genomic Regions in Rearrangement Distance Estimation.
Genome biology and evolution - 22 May 2016
Biller Priscila, Guéguen Laurent, Knibbe Carole, Tannier Eric
Abstract excerpt
Models of evolution by genome rearrangements are prone to two types of flaws: One is to ignore the diversity of susceptibility to breakage across genomic regions, and the other is to suppose that susceptibility values are given. Without necessarily supposing their precise localization, we call "solid" the regions that are improbably broken by rearrangements and "fragile" the regions outside solid ones. We propose...
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