Fast and accurate phylogenetic reconstruction from high-resolution whole-genome data and a novel robustness estimator.

Abstract excerpt

The rapid accumulation of whole-genome data has renewed interest in the study of genomic rearrangements. Comparative genomics, evolutionary biology, and cancer research all require models and algorithms to elucidate the mechanisms, history, and consequences of these rearrangements. However, even simple models lead to NP-hard problems, particularly in the area of phylogenetic analysis. Current approaches are...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Computer Simulation
• Share to Data Interpretation, Statistical