Article

Chromosomal Inversion Symmetry: Generalized Chargaff Rules

2015-01-14

Abstract excerpt

The generalization of the second Chargaff rule to values of k larger than 1, states that the frequency of any k-mer on a single strand almost equals that of its inverse (reverse-complement). We demonstrate the validity of the generalized rule up to k=10 for all human chromosomes. Moreover, this Inversion Symmetry holds for many species, both eukaryotes and prokaryotes, for ranges of k which may vary from 7 to 10...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 04c17f1e-f2b3-5ad0-8c88-00307a25a61a
DOI: 10.1101/013789

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Chromosomal Inversion Symmetry: Generalized Chargaff RulesDOI 10.1101/013789Read

Inter-chromosomal K-mer DistancesSemantic proximity Read

Chargaff's legacy.Semantic proximity Read

Chargaff's second parity rule lies at the origin of additive genetic interactions in quantitative traits to make omnigenic selection possible.Semantic proximity Read

Drake's rule as a consequence of approaching channel capacity.Semantic proximity Read

Genomic duplications shaped current retrotransposon position distribution in humanSemantic proximity Read

A Model-Driven Quantitative Analysis of Retrotransposon Distributions in the Human Genome.Semantic proximity Read

Chromosome evolution with naked eye: palindromic context of the life origin.Semantic proximity Read

Detection and validation of single gene inversions.Semantic proximity Read

Shannon information in complete genomes.Semantic proximity Read

The organization of biological sequences into constrained and unconstrained parts determines fundamental properties of genotype-phenotype maps.Semantic proximity Read

Shannon information in complete genomes.Semantic proximity Read

Evolution of ultraconserved elements by indelsSemantic proximity Read