Article
Hodgkin lymphoma variant of Richter transformation: morphology, Epstein-Barr virus status, clonality, and survival analysis-with comparison to Hodgkin-like lesion.
Human pathology - 1 Sept 2016
Xiao Wenbin, Chen Wayne W, Sorbara Lynn, Davies-Hill Theresa, Pittaluga Stefania, Raffeld Mark, Jaffe Elaine S
Abstract excerpt
Hodgkin/Reed-Sternberg (HRS) cells in the setting of chronic lymphocytic leukemia (CLL) exist in 2 forms: type I with isolated HRS cells in a CLL background (Hodgkin-like lesion) and type II with typical classic Hodgkin lymphoma, a variant of Richter transformation (CHL-RT). The clinical significance of the 2 morphological patterns is unclear, and their biological features have not been compared. We...
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