Article
[Clonality analysis and mutational status of IgVH gene in Hodgkin variant of Richter syndrome].
Zhonghua bing li xue za zhi = Chinese journal of pathology - 1 Aug 2008
Mao Zheng-rong, Rosenwald Andreas, Zhang Suo-jiang, Zhou Ren, Mueller-Hermelink Hans Konrad
Abstract excerpt
OBJECTIVE: To detect the clonal relationship, the rearrangement, and the mutational status of IgVH gene; the influence of these molecular characteristics on the clinical outcome in Hodgkin variant of Richter syndrome; and the possible molecular pathogenesis in this transformation. METHODS: The clonal rearrangements and mutational status of IgVH genes were analyzed in Hodgkin variant of Richter syndrome and B-CLL...
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