Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Impact of sex and APOE4 on cerebral amyloid angiopathy in Alzheimer's disease.

Acta neuropathologica - 1 Aug 2016

Shinohara Mitsuru, Murray Melissa E, Frank Ryan D, Shinohara Motoko, DeTure Michael, Yamazaki Yu, Tachibana Masaya, Atagi Yuka, Davis Mary D, Liu Chia-Chen, Zhao Na, Painter Meghan M, Petersen Ronald C, Fryer John D, Crook Julia E, Dickson Dennis W, Bu Guojun, Kanekiyo Takahisa

Abstract excerpt

Cerebral amyloid angiopathy (CAA) often coexists with Alzheimer's disease (AD). APOE4 is a strong genetic risk factor for both AD and CAA. Sex-dependent differences have been shown in AD as well as in cerebrovascular diseases. Therefore, we examined the effects of APOE4, sex, and pathological components on CAA in AD subjects. A total of 428 autopsied brain samples from pathologically confirmed AD cases were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer Disease
Share to Amyloid beta-Peptides

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Apolipoprotein E4

Share to Cerebral Amyloid Angiopathy

Share to Neurofibrillary Tangles

Share to Plaque, Amyloid

Share to Sex Characteristics

Source

Open in PubMed Open full text

Identifiers

PMID: 27179972
DOI: 10.1007/s00401-016-1580-y
PMCID: PMC4947445

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Impact of sex and APOE4 on cerebral amyloid angiopathy in Alzheimer's disease.PMID 27179972Read ↗

Alzheimer's disease pathology influences severity and topographical distribution of cerebral amyloid angiopathy.Semantic proximity Read ↗

Deciphering the role of APOE in cerebral amyloid angiopathy: from genetic insights to therapeutic horizons.Semantic proximity Read ↗

Factors associated with intracerebral hemorrhage in confirmed cerebral amyloid angiopathy.Semantic proximity Read ↗

Cerebral amyloid angiopathy and Alzheimer's and related pathologies across APOE genotypes.Semantic proximity Read ↗

Clinical predictors of severe cerebral amyloid angiopathy and influence of APOE genotype in persons with pathologically verified Alzheimer disease.Semantic proximity Read ↗

Capillary cerebral amyloid angiopathy identifies a distinct APOE epsilon4-associated subtype of sporadic Alzheimer's disease.Semantic proximity Read ↗

Relationship between severe amyloid angiopathy, apolipoprotein E genotype, and vascular lesions in Alzheimer's disease.Semantic proximity Read ↗

Two types of sporadic cerebral amyloid angiopathy.Semantic proximity Read ↗

APOE-mediated sex differences in microvascular pathology and AD-associated proteinopathies in the medial temporal lobe.Semantic proximity Read ↗

APOE associations with severe CAA-associated vasculopathic changes: collaborative meta-analysis.Semantic proximity Read ↗

Insights into the pathogenesis and pathogenicity of cerebral amyloid angiopathy.Semantic proximity Read ↗

Association between apolipoprotein E e4 allele and arteriosclerosis, cerebral amyloid angiopathy, and cerebral white matter damage in Alzheimer's disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.