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Collagen type VI α5 gene variations may predict the risk of lung cancer development in Chinese Han population.

Scientific reports - 19 Mar 2020

Duan Ying, Liu Gaowen, Sun Yao, Wu Jiamin, Xiong Zichao, Jin Tianbo, Chen Mingwei

Abstract excerpt

The abundant expression of collagen type VI α5 (COL6A5) exists in lung tissue, and its role in lung cancer is still unknown. We performed a genetic association study with an attempt to detect the relationships between single nucleotide polymorphisms (SNPs) in COL6A5 and lung cancer predisposition in Chinese Han population. We finally selected six tag-SNPs to determine their genotypes among 510 lung cancer...

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PMID: 32193401
DOI: 10.1038/s41598-020-61614-x
PMCID: PMC7081318

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