Article
Family study of monozygotic twins affected by pemphigus vulgaris.
Human immunology - 1 Jul 2016
Salathiel Adriana Martinelli, Brochado Maria José Franco, Kim Olivia, Deghaide Neifi Hassan Saloum, Donadi Eduardo Antonio, Roselino Ana Maria
Abstract excerpt
Rare are the family studies that include siblings affected by pemphigus vulgaris (PV) and in whom HLA class II alleles are related. HLA-DR and -DQ genotyping and profiling of antibodies against desmogleins (Dsg) 1 and Dsg3 were performed in ten members of a family including monozygotic twins affected by PV. The twin sisters were heterozygotes; they presented the haplotypes most commonly associated with increased...
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