Article
Human leukocyte antigen genotypes and antibody profiles associated with familial pemphigus in Japanese.
The Journal of dermatology - 1 Jul 2011
Yamamoto Tetsuya, Ikeda Kazuko, Sasaoka Shunsuke, Yamasaki Osamu, Fujimoto Wataru, Aoyama Yumi, Iwatsuki Keiji
Abstract excerpt
Previous population-based, genetic studies have shown that human leukocyte antigen (HLA) class II loci such as HLA-DR4 (DRB1*04) and HLA-DR14 (DRB1*14) alleles are consistently associated with the occurrence of pemphigus vulgaris (PV) in Japanese as well as other ethnic populations. Among PV-related HLA-DRB1 alleles (*0406, *1401, *1405, *1406) in Japan, HLA DRB1*1405 and DRB1*0406 were found to be associated...
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