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Article

The association of IL-18 gene promoter polymorphisms and the levels of serum IL-18 on the risk of multiple sclerosis.

Clinical neurology and neurosurgery - 1 Jul 2016

Orhan Gürdal, Eruyar Esra, Mungan Semra Öztürk, Ak Fikri, Karahalil Bensu

Abstract excerpt

OBJECTIVES: Multiple sclerosis is an inflammatory condition of the central nervous system whose etiology is influenced by immunologic, genetic, and environmental factors. Aim of the present study was to determine if any relation exists between IL-18 -137C/G and -607C/A gene promoter polymorphisms on the individual susceptibility of multiple sclerosis and also to investigate the possible effect of IL-18 activity...

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Identifiers

PMID: 27177146
DOI: 10.1016/j.clineuro.2016.04.027

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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