Article
Interleukin 18 gene polymorphism is a risk factor for multiple sclerosis.
Molecular biology reports - 1 Mar 2014
Karakas Celik Sevim, Öz Zehra Safi, Dursun Ahmet, Unal Aysun, Emre Ufuk, Cicek Salih, Keni Fatih Mehmet
Abstract excerpt
Proinflammatory cytokines with immunosuppressive properties play an important role in the pathogenesis of multiple sclerosis (MS). Interleukin 18 (IL-18) is one of the most important innate cytokines produced from macrophages in the early stages of the inflammatory immune response. The purpose of this study was to determine whether there was any relationship between IL18 gene polymorphisms and MS. IL18 genotyping...
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