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Interleukin 18 polymorphisms and its serum level in patients with multiple sclerosis

1 Jan 2019

Abstract excerpt

BACKGROUND: Multiple sclerosis (MS) is a chronic demyelinating disorder of central nervous system. Although the definite pathogenesis of MS has not been understood, crucial role of environmental and genetic risk factors has been proposed. PROPOSE: To determine the serum level of interleukin-18 (IL-18) as well as gene polymorphisms of IL-18 (rs1946518, rs360719, and rs187238). METHODS: In this case-control study,...

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PMID: 31736573
DOI: 10.4103/aian.aian_515_18

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