Article
Upregulation of connexin43 gap junctions between smooth muscle cells after balloon catheter injury in the rat carotid artery.
Arteriosclerosis, thrombosis, and vascular biology - 1 Nov 1997
Yeh H I, Lupu F, Dupont E, Severs N J
Abstract excerpt
Phenotypic transformation of smooth muscle cells (SMCs) to the synthetic state in vitro and in human coronary atherosclerosis is reported to be associated with upregulation of connexin43 gap junctions. To determine whether cellular interactions mediated by gap junctions participate in the phenotypic transformation of SMCs in arterial injury and disease in general and to establish the spatial and temporal pattern...
Topics
- Angioplasty, Balloon
- Animals
- Carotid Arteries
- Carotid Artery Injuries
- Connexin 43
- Gap Junctions
- Image Processing, Computer-Assisted
- Male
- Microscopy, Confocal
- Microscopy, Fluorescence
- Muscle, Smooth, Vascular
- Phenotype
- Rats
- Rats, Sprague-Dawley
- Tunica Intima
- Up-Regulation