Article
Angiogenesis genotyping in the selection of first-line treatment with either sunitinib or pazopanib for advanced renal cell carcinoma.
Oncotarget - 21 Jun 2016
Bianconi Maristella, Faloppi Luca, Loretelli Cristian, Zizzi Antonio, Giampieri Riccardo, Bittoni Alessandro, Andrikou Kalliopi, Del Prete Michela, Burattini Luciano, Montironi Rodolfo, Scartozzi Mario, Cascinu Stefano
Abstract excerpt
INTRODUCTION: Recent data from the COMPARZ study seem to suggest a non-inferiority of pazopanib confronted with sunitinib in PFS and OS. We previously reported how VEGF and VEGFR polymorphisms might have a predictive role in patients treated with first-line sunitinib. Aim of our study was to investigate whether tumour angiogenesis genotyping could influence clinical outcome in RCC patients treated with either...
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