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Article

Genetic Determinants of the Gut Microbiome in UK Twins.

Cell host & microbe - 11 May 2016

Goodrich Julia K, Davenport Emily R, Beaumont Michelle, Jackson Matthew A, Knight Rob, Ober Carole, Spector Tim D, Bell Jordana T, Clark Andrew G, Ley Ruth E

Abstract excerpt

Studies in mice and humans have revealed intriguing associations between host genetics and the microbiome. Here we report a 16S rRNA-based analysis of the gut microbiome in 1,126 twin pairs, a subset of which was previously reported. Tripling the sample narrowed the confidence intervals around heritability estimates and uncovered additional heritable taxa, some of which are validated in other studies. Repeat...

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Identifiers

PMID: 27173935
DOI: 10.1016/j.chom.2016.04.017
PMCID: PMC4915943

Genes

ALDH1L1
LCT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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