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Article

Affinity improvement by fine tuning of single-chain variable fragment against aflatoxin B1.

Food chemistry - 15 Oct 2016

Min Won-Ki, Na Kang-In, Yoon Jung-Hyun, Heo Yoon-Jee, Lee Daesang, Kim Sung-Gun, Seo Jin-Ho

Abstract excerpt

Aflatoxin B1 (AFB1) produced in Aspergillus flavus is a major hepatocarcinogen found in foods and feed. For effective immunological detection of AFB1 at low concentrations, the development of high affinity antibody for AFB1 is required. Previously, an affinity-maturated single-chain variable fragment containing 6 mutations (scFv-M37) was isolated from an artificial mutagenic library, which showed a 9-fold higher...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27173568
DOI: 10.1016/j.foodchem.2016.04.085

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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