Article
Physical Activity and Bone Accretion: Isotemporal Modeling and Genetic Interactions.
Medicine and science in sports and exercise - 1 May 2018
Mitchell Jonathan A, Chesi Alessandra, McCormack Shana E, Cousminer Diana L, Kalkwarf Heidi J, Lappe Joan M, Gilsanz Vicente, Oberfield Sharon E, Shepherd John A, Kelly Andrea, Grant Struan F A, Zemel Babette S
Abstract excerpt
PURPOSE: This study aimed to determine if replacing time spent in high- and low-impact physical activity (PA) predicts changes in pediatric bone mineral density (BMD) and content (BMC). METHODS: We analyzed data from the longitudinal Bone Mineral Density in Childhood Study (N = 2337 with up to seven visits). The participants were age 5-19 yr at baseline, 51.2% were female, and 80.6% were nonblack. Spine, total...
Topics
- Adolescent
- Alleles
- Bone Density
- Bone and Bones
- Child
- Child, Preschool
- Exercise
- Female
- Humans
- Male
- Models, Theoretical
- Wnt Signaling Pathway