Article
The circadian clock regulates autophagy directly through the nuclear hormone receptor Nr1d1/Rev-erbα and indirectly via Cebpb/(C/ebpβ) in zebrafish.
Autophagy - 2 Aug 2016
Huang Guodong, Zhang Fanmiao, Ye Qiang, Wang Han
Abstract excerpt
Autophagy is a highly conserved intracellular degradation system, and recently was shown to display circadian rhythms in mice. The mechanisms underlying circadian regulation of autophagy, however, are still unclear. Here, we observed that numbers of autophagosomes and autolysosomes exhibit daily rhythms in the zebrafish liver, and cebpb/(c/ebpβ) and various autophagy genes are rhythmically expressed in zebrafish...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
