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Article

Diurnal Rhythmicity of Autophagy Is Impaired in the Diabetic Retina

7 Apr 2020

Abstract excerpt

Retinal homeostasis is under both diurnal and circadian regulation. We sought to investigate the diurnal expression of autophagy proteins in normal rodent retina and to determine if this is impaired in diabetic retinopathy. C57BL/6J mice and Bio-Breeding Zucker (BBZ) rats were maintained under a 12h/12h light/dark cycle and eyes, enucleated over a 24 h period. Eyes were also collected from diabetic mice with two...

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PMID: 32272782
DOI: 10.3390/cells9040905

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