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Quantitative analysis of 3D extracellular matrix remodelling by pancreatic stellate cells

11 May 2016

Abstract excerpt

Extracellular matrix (ECM) remodelling is integral to numerous physiological and pathological processes in biology, such as embryogenesis, wound healing, fibrosis and cancer. Until recently, most cellular studies have been conducted on 2D environments where mechanical cues significantly differ from physiologically relevant 3D environments, impacting cellular behaviour and masking the interpretation of cellular...

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PMID: 27170254
DOI: 10.1242/bio.017632

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