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Article

Lipid Flippase Subunit Cdc50 Mediates Drug Resistance and Virulence in Cryptococcus neoformans.

mBio - 10 May 2016

Huang Wei, Liao Guojian, Baker Gregory M, Wang Yina, Lau Richard, Paderu Padmaja, Perlin David S, Xue Chaoyang

Abstract excerpt

UNLABELLED: Cryptococcus neoformans is a human fungal pathogen and a major cause of fungal meningitis in immunocompromised individuals. Treatment options for cryptococcosis are limited. Of the two major antifungal drug classes, azoles are active against C. neoformans but exert a fungistatic effect, necessitating long treatment regimens and leaving open an avenue for emergence of azole resistance. Drugs of the...

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Source

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Identifiers

PMID: 27165800
DOI: 10.1128/mBio.00478-16
PMCID: PMC4959666

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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