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Article

Plasma Screening for Progranulin Mutations in Patients with Progressive Supranuclear Palsy and Corticobasal Syndromes.

Journal of Alzheimer's disease : JAD - 4 May 2016

Galimberti Daniela, Bertram Kelly, Formica Alessandra, Fenoglio Chiara, Cioffi Sara M G, Arighi Andrea, Scarpini Elio, Colosimo Carlo

Abstract excerpt

Progranulin gene (GRN) mutations are characterized by heterogeneous presentations. Corticobasal syndrome (CBS) is often associated with GRN mutations, whereas association with progressive supranuclear palsy syndrome (PSPS) is rare. Plasma progranulin levels were evaluated in 34 patients, including 19 with PSPS, 12 with CBS, and 3 with mixed signs, with the purpose to screen for the presence of causal mutations,...

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Source

Identifiers

PMID: 27163816
DOI: 10.3233/JAD-160073

Genes

CBS
GRN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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