Article
The UbiI (VisC) Aerobic Ubiquinone Synthase Is Required for Expression of Type 1 Pili, Biofilm Formation, and Pathogenesis in Uropathogenic Escherichia coli.
Journal of bacteriology - 1 Oct 2016
Floyd Kyle A, Mitchell Courtney A, Eberly Allison R, Colling Spencer J, Zhang Ellisa W, DePas William, Chapman Matthew R, Conover Matthew, Rogers Bridget R, Hultgren Scott J, Hadjifrangiskou Maria
Abstract excerpt
UNLABELLED: Uropathogenic Escherichia coli (UPEC), which causes the majority of urinary tract infections (UTI), uses pilus-mediated adherence to initiate biofilm formation in the urinary tract. Oxygen gradients within E. coli biofilms regulate expression and localization of adhesive type 1 pili. A transposon mutant screen for strains defective in biofilm formation identified the ubiI (formerly visC) aerobic...
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