Article
Exploiting Mouse Models to Study Ras-Induced Cutaneous Squamous Cell Carcinoma.
The Journal of investigative dermatology - 1 Aug 2016
Lowry William E, Flores Aimee, White Andrew C
Abstract excerpt
Recently developed methods have allowed for the delivery of cancer-causing genetic mutations to particular cell types in the epidermis in an inducible fashion. These methods have allowed for sophisticated explorations on the cellular and molecular origins of squamous cell carcinoma due to oncogenic mutations in Ras. These experiments have provided insights into whether cancer is initiated by stem or more...
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