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Article

Autophagy stimulation by rapamycin suppresses lung inflammation and infection by Burkholderia cenocepacia in a model of cystic fibrosis.

Autophagy - 1 Nov 2011

Abdulrahman Basant A, Khweek Arwa Abu, Akhter Anwari, Caution Kyle, Kotrange Sheetal, Abdelaziz Dalia H A, Newland Christie, Rosales-Reyes Roberto, Kopp Benjamin, McCoy Karen, Montione Richard, Schlesinger Larry S, Gavrilin Mikhail A, Wewers Mark D, Valvano Miguel A, Amer Amal O

Abstract excerpt

Cystic fibrosis (CF) is the most common inherited lethal disease of Caucasians which results in multi organ dysfunction. However, 85% of the deaths are due to pulmonary infections. Infection by Burkholderia cenocepacia (B. cepacia) is a particularly lethal threat to CF patients because it causes...

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Identifiers

PMID: 21997369
DOI: 10.4161/auto.7.11.17660
PMCID: PMC3359483

Genes

CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21997369-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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