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Refined Phenotyping of Modic Changes: Imaging Biomarkers of Prolonged Severe Low Back Pain and Disability.

Medicine - 1 May 2016

Määttä Juhani H, Karppinen Jaro, Paananen Markus, Bow Cora, Luk Keith D K, Cheung Kenneth M C, Samartzis Dino

Abstract excerpt

Low back pain (LBP) is the world's most disabling condition. Modic changes (MC) are vertebral bone marrow changes adjacent to the endplates as noted on magnetic resonance imaging. The associations of specific MC types and patterns with prolonged, severe LBP and disability remain speculative. This study assessed the relationship of prolonged, severe LBP and back-related disability, with the presence and morphology...

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Disability Evaluation
Incidence
Life Style
Low Back Pain
Lumbar Vertebrae

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pain Measurement

Persons with Disabilities

Severity of Illness Index

Source

Open in PubMed Open full text

Identifiers

PMID: 27258491
DOI: 10.1097/MD.0000000000003495
PMCID: PMC4900699

Genes

LBP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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Refined Phenotyping of Modic Changes: Imaging Biomarkers of Prolonged Severe Low Back Pain and Disability.PMID 27258491Read ↗

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