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Article

Insights into RpoB clinical mutants in mediating rifampicin resistance in Mycobacterium tuberculosis.

Journal of molecular graphics & modelling - 1 Jun 2016

Nusrath Unissa Ameeruddin, Hassan Sameer, Indira Kumari Venkatesan, Revathy Ravi, Hanna Luke Elizabeth

Abstract excerpt

Rifampicin (RIF) an essential first-line anti-tuberculosis (TB) drug, resistance to RIF is a potential threat to TB control program and widely considered as surrogate marker for detection of multi-drug resistant-TB (MDR-TB), molecular understanding of which is the utmost need of the hour. Mutations at RIF resistance-determining region (RRDR) of 81-bp in the rpoB gene coding for β subunit or RpoB protein is the...

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Identifiers

PMID: 27155814
DOI: 10.1016/j.jmgm.2016.04.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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