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Application of Computational Methods in Understanding Mutations in Mycobacterium tuberculosis Drug Resistance

28 Sept 2021

Abstract excerpt

The emergence of drug-resistant strains of Mycobacterium tuberculosis (Mtb) impedes the End TB Strategy by the World Health Organization aiming for zero deaths, disease, and suffering at the hands of tuberculosis (TB). Mutations within anti-TB drug targets play a major role in conferring drug resistance within Mtb; hence, computational methods and tools are being used to understand the mechanisms by which they...

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PMID: 34651013
DOI: 10.3389/fmolb.2021.643849

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