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Article

Creb1 regulates late stage mammalian lung development via respiratory epithelial and mesenchymal-independent mechanisms.

Scientific reports - 6 May 2016

Antony N, McDougall A R, Mantamadiotis T, Cole T J, Bird A D

Abstract excerpt

During mammalian lung development, the morphological transition from respiratory tree branching morphogenesis to a predominantly saccular architecture, capable of air-breathing at birth, is dependent on physical forces as well as molecular signaling by a range of transcription factors including the cAMP response element binding protein 1 (Creb1). Creb1(-/-) mutant mice exhibit complete neonatal lethality...

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PMID: 27150575
DOI: 10.1038/srep25569
PMCID: PMC4858709

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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