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Article

Which melanoma patient carries a BRAF-mutation? A comparison of predictive models.

Oncotarget - 14 Jun 2016

Eigentler Thomas, Assi Zeinab, Hassel Jessica C, Heinzerling Lucie, Starz Hans, Berneburg Mark, Bauer Jürgen, Garbe Claus

Abstract excerpt

BACKGROUND: In patients with advanced melanoma the detection of BRAF mutations is considered mandatory before the initiation of an expensive treatment with BRAF/MEK inhibitors. Sometimes it is difficult to perform such an analysis if archival tumor tissue is not available and fresh tissue has to be collected. RESULTS: 514 of 1170 patients (44%) carried a BRAF mutation. All models revealed age and histological...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27150060
DOI: 10.18632/oncotarget.9143
PMCID: PMC5094988

Genes

BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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