Article
Is BRAF a prognostic factor in stage III skin melanoma? A retrospective study of 72 patients after positive sentinel lymph node dissection.
The British journal of dermatology - 1 Jul 2014
Picard M, Pham Dang N, D'Incan M, Mansard S, Dechelotte P, Pereira B, Mondie J M, Barthelemy I
Abstract excerpt
BACKGROUND: BRAF was identified as an oncogene in skin melanoma in 2002, and since 2011 has been a therapeutic target in the treatment of metastatic melanoma. The role of BRAF mutation in tumour initiation and the disease course remains to be elucidated. OBJECTIVES: The main objective of our study was to determine whether there is a relationship between BRAF status and overall survival in patients with a melanoma...
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