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Identification of genetic variants in TNF receptor 2 which are associated with the development of cervical carcinoma.

Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals - 1 Nov 2016

Singhal Pallavi, Sharma Upma, Hussain Showket, Nag Alo, Bharadwaj Mausumi

Abstract excerpt

Cervical cancer is one of the most common malignancies among women in India. Beside HPV, other factors present in host also put their role in the progression of cervical tumerogenesis. In present study, we screened 300 subjects to identify variations in TNFR2 gene by PCR-dHPLC method followed by direct sequencing. We identified six known and four novel variations in six different exons of TNFR2 gene. Out of these...

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Identifiers

PMID: 27145290
DOI: 10.3109/1354750X.2016.1172109

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TNF

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