Article
Cyclooxygenase-2 gene polymorphisms and risk of cervical cancer in a North Indian population.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 1 May 2010
Pandey Saumya, Mittal Rama Devi, Srivastava Madhu, Srivastava Kirti, Mittal Balraj
Abstract excerpt
INTRODUCTION: Single nucleotide polymorphisms in the cyclooxygenase-2 (COX-2) might contribute to differential COX-2 expression and subsequent interindividual variability in susceptibility to cancer. This study sought to evaluate the effects of COX-2 +8473T/C (rs5275) and -765G/C (rs20417) gene polymorphisms on the risk of cervical cancer in women of Northern India. METHODS: Peripheral blood samples were...
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