Article
Tumor Necrosis Factor Alpha (-238 / -308) and TNFRII-VNTR (-322) Polymorphisms as Genetic Biomarkers of Susceptibility to Develop Cervical Cancer Among Tunisians.
Pathology oncology research : POR - 1 Apr 2015
Zidi Sabrina, Stayoussef Mouna, Zouidi Ferjeni, Benali Samir, Gazouani Ezzedine, Mezlini Amel, Yacoubi-Loueslati Besma
Abstract excerpt
Host genetic factors may confer susceptibility to Cervical Cancer. TNF-α as pro-inflammatory cytokine participates in the maintenance of immune homeostasis. Allelic variation of immuno-modulatory genes is associated with alteration in immune function. This study investigated the associations between TNF-α-308G>A, -238G>A, and TNFRII - VNTR-322 and cervical cancer in Tunisian women. Genotypes of those...
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