TNF-alpha rs1800629 polymorphism is not associated with HPV infection or cervical cancer in the Chinese population.

doi:10.1371/journal.pone.0045246

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Article

TNF-alpha rs1800629 polymorphism is not associated with HPV infection or cervical cancer in the Chinese population.

PloS one - 1 Jan 2012

Wang Ning, Yin Duo, Zhang Shulan, Wei Heng, Wang Shizhuo, Zhang Yang, Lu Yanming, Dai Shuyan, Li Wei, Zhang Qiao, Zhang Yao

Abstract excerpt

BACKGROUND: While HPV infection is the main cause of cervical cancer, genetic susceptibility to HPV infection is not well understood. Tumor necrosis factor alpha (TNF-alpha), involved in the defense against HPV infection, plays an important role in cervical cancer progression and regression. The aim of this study was to investigate the relationship between the TNF-alpha rs1800629 polymorphism and risk of HPV...

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PMID: 23028877
DOI: 10.1371/journal.pone.0045246
PMCID: PMC3441631

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