Article
The relationship of vascular endothelial growth factor gene polymorphisms and clinical outcome in advanced gastric cancer patients treated with FOLFOX: VEGF polymorphism in gastric cancer.
BMC cancer - 1 Feb 2013
Oh Sung Yong, Kwon Hyuk-Chan, Kim Sung Hyun, Lee Suee, Lee Ji Hyun, Hwang Jung-Ah, Hong Seung Hyun, Graves Christian A, Camphausen Kevin, Kim Hyo-Jin, Lee Yeon-Su
Abstract excerpt
BACKGROUND: The aim of this study is to evaluate the associations between vascular endothelial growth factor (VEGF) Single-nucleotide polymorphisms (SNPs) and clinical outcome in advanced gastric cancer patients treated with oxaliplatin, 5-fluorouracil, and leucovorin (FOLFOX). METHODS: Genomic DNA was isolated from whole blood, and six VEGF (-2578C/A, -2489C/T, -1498 T/C, -634 G/C, +936C/T, and +1612 G/A) gene...
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