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Cell‐free circulating tumour DNA as a liquid biopsy in breast cancer

17 Dec 2015

Abstract excerpt

Recent developments in massively parallel sequencing and digital genomic techniques support the clinical validity of cell-free circulating tumour DNA (ctDNA) as a 'liquid biopsy' in human cancer. In breast cancer, ctDNA detected in plasma can be used to non-invasively scan tumour genomes and quantify tumour burden. The applications for ctDNA in plasma include identifying actionable genomic alterations, monitoring...

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PMID: 26776681
DOI: 10.1016/j.molonc.2015.12.001

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