Article
Sliding of centrosome-unattached microtubules defines key features of neuronal phenotype.
The Journal of cell biology - 9 May 2016
Rao Anand N, Falnikar Aditi, O'Toole Eileen T, Morphew Mary K, Hoenger Andreas, Davidson Michael W, Yuan Xiaobing, Baas Peter W
Abstract excerpt
Contemporary models for neuronal migration are grounded in the view that virtually all functionally relevant microtubules (MTs) in migrating neurons are attached to the centrosome, which occupies a position between the nucleus and a short leading process. It is assumed that MTs do not undergo independent movements but rather transduce forces that enable movements of the centrosome and nucleus. The present results...
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