Article
Tau-induced traffic jams reflect organelles accumulation at points of microtubule polar mismatching.
Traffic (Copenhagen, Denmark) - 1 Apr 2008
Shemesh Or A, Erez Hadas, Ginzburg Irith, Spira Micha E
Abstract excerpt
It is currently accepted that tau overexpression leads to impaired organelle transport and thus to neuronal degeneration. Nevertheless, the underlying mechanisms that lead to impaired organelle transport are not entirely clear. Using cultured Aplysia neurons and online confocal imaging of human t...
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