Article
Drug resistance mutations after the first 12 months on antiretroviral therapy and determinants of virological failure in Rwanda.
Tropical medicine & international health : TM & IH - 1 Jul 2016
Ndahimana Jean d'Amour, Riedel David J, Mwumvaneza Mutagoma, Sebuhoro Dieudone, Uwimbabazi Jean Claude, Kubwimana Marthe, Mugabo Jules, Mulindabigwi Augustin, Kirk Catherine, Kanters Steve, Forrest Jamie I, Jagodzinski Linda L, Peel Sheila A, Ribakare Muhayimpundu, Redfield Robert R, Nsanzimana Sabin
Abstract excerpt
OBJECTIVE: To evaluate HIV drug resistance (HIVDR) and determinants of virological failure in a large cohort of patients receiving first-line tenofovir-based antiretroviral therapy (ART) regimens. METHODS: A nationwide retrospective cohort from 42 health facilities was assessed for virological failure and development of HIVDR mutations. Data were collected at ART initiation and at 12 months of ART on patients...
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