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Article

Drug Resistance Among Adolescents and Young Adults with Virologic Failure of First-Line Antiretroviral Therapy and Response to Second-Line Treatment.

AIDS research and human retroviruses - 1 Jul 2020

Kouamou Vinie, Varyani Bhavini, Shamu Tinei, Mapangisana Tichaona, Chimbetete Cleophas, Mudzviti Tinashe, Manasa Justen, Katzenstein David

Abstract excerpt

Barriers to sustainable virologic suppression (VS) of HIV-infected adolescents and young adults include drug resistance mutations (DRMs) and limited treatment options, which may impact the outcome of second-line antiretroviral therapy (ART). We sequenced plasma viral RNA from 74 adolescents and young adults (16-24 years) failing first-line ART at Newlands Clinic, Zimbabwe between October 2015 and December 2016....

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Identifiers

PMID: 32138527
DOI: 10.1089/AID.2019.0232

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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