Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mendelian randomization study reveals a population-specific putative causal effect of type 2 diabetes in risk of cataract.

International journal of epidemiology - 6 Jan 2022

Zhang Haoyang, Xiu Xuehao, Xue Angli, Yang Yuedong, Yang Yuanhao, Zhao Huiying

Abstract excerpt

BACKGROUND: The epidemiological association between type 2 diabetes and cataract has been well established. However, it remains unclear whether the two diseases share a genetic basis, and if so, whether this reflects a putative causal relationship. METHODS: We used East Asian population-based genome-wide association studies (GWAS) summary statistics of type 2 diabetes (Ncase = 36 614, Ncontrol = 155 150) and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cataract
Share to Causality

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Connexins and lens biology

Share to Diabetes Mellitus, Type 2

Share to Genetic Associations and Epidemiology

Share to Genome-Wide Association Study

Share to Mendelian Randomization Analysis

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 34999863
DOI: 10.1093/ije/dyab175

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mendelian randomization study reveals a population-specific putative causal effect of type 2 diabetes in risk of cataract.PMID 34999863Read ↗

The putative causal effect of type 2 diabetes in risk of cataract: a Mendelian randomization study in East AsianSemantic proximity Read ↗

Sex differences in the risk of cataract associated with type 2 diabetes: a Mendelian randomization studySemantic proximity Read ↗

A Genetic Perspective on Diabetic Complications: A Mendelian Randomization Study on the Increased Risk of Cataracts in Type 1 DiabetesSemantic proximity Read ↗

Genetic Correlation and Mendelian Randomization Analyses Reveal Causal Links Between Metabolic-Associated Diseases or Risk Factors and Major Eye Diseases.Semantic proximity Read ↗

[Association between type 2 diabetes mellitus and the risk of developing cataracts: based on the research of two-sample Mendelian randomization].Semantic proximity Read ↗

Dissecting causal associations of type 2 diabetes with 111 types of ocular conditions: a Mendelian randomization studySemantic proximity Read ↗

Novel susceptibility genes associated with diabetic cataract in a Taiwanese population.Semantic proximity Read ↗

Association of Behavioral and Clinical Risk Factors With Cataract: A Two-Sample Mendelian Randomization Study.Semantic proximity Read ↗

Integrative multi-omics quantitative trait loci prioritize CASP7 as a candidate protective gene for cataract.Semantic proximity Read ↗

Causal relationship between glycemic traits and inflammatory eye diseases and their complications, and myopia: a Mendelian randomization analysisSemantic proximity Read ↗

Uncovering Novel Genetic Loci and Biological Pathways Associated with Age-Related Cataracts through GWAS Meta-AnalysisSemantic proximity Read ↗

Identification of Putative Causal Relationships Between Type 2 Diabetes and Blood-Based Biomarkers in East Asians by Mendelian Randomization.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.