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Article

Rearrangement of Influenza Virus Spliced Segments for the Development of Live-Attenuated Vaccines

28 Apr 2016

Abstract excerpt

UNLABELLED: Influenza viral infections represent a serious public health problem, with influenza virus causing a contagious respiratory disease which is most effectively prevented through vaccination. Segments 7 (M) and 8 (NS) of the influenza virus genome encode mRNA transcripts that are alternatively spliced to express two different viral proteins. This study describes the generation, using reverse genetics, of...

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Identifiers

PMID: 27122587
DOI: 10.1128/jvi.00410-16

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