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Article

Expansion of Bone Precursors through Jun as a Novel Treatment for Osteoporosis-Associated Fractures.

Stem cell reports - 14 Apr 2020

Lerbs Tristan, Cui Lu, Muscat Claire, Saleem Atif, van Neste Camille, Domizi Pablo, Chan Charles, Wernig Gerlinde

Abstract excerpt

Osteoporosis and osteoporotic fractures lead to decreased life quality and high healthcare costs. Current treatments prevent losses in bone mass and fractures to some extent but have side effects. Therefore, better therapies are needed. This study investigated whether the transcription factor Jun has a specific pro-osteogenic potency and whether modulating Jun could serve as a novel treatment for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32197115
DOI: 10.1016/j.stemcr.2020.02.009
PMCID: PMC7160304

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